Unless I get totally off the grid, it is tough for me to relax and not think of business on vacation. For better or worse I have closely integrated my business and personal life. But Beth Silver at Doubet Consulting writes a great article with suggestions on taking time off.
I especially like this advice!
"If you are able to schedule a quiet day in the office for yourself, before your official return, do so. By telling clients that you will be back on Tuesday, when you will really be in the office Monday, allows you to answer those emails and return some of your calls without the stress of being rushed."